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Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies

✍ Scribed by Paul D. Gottlieb; Ann Marshak-Rothstein; Karen Auditore-Hargreaves; Dorothy B. Berkoben; Deborah A. August; Roger M. Rosche; James D. Benedetto

Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
870 KB
Volume
10
Category
Article
ISSN
0093-7711

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## Abstract Monoclonal anti‐Lyt‐1.1 alloantibody was produced as tissue culture supernatant and administered to mice. The antibody, given intraperitoneally, resulted in the suppression of all T cell functions studied, but was without direct effect on B cells. Thus, skin and tumor allograft survival