Construction and characterization of a high activity mutant of human keratinocyte growth factor-2
โ Scribed by Jinfeng Wang; Xin Cai; Minji Zou; Tao Xu; Shen Liu; Yuanyuan Wang; Jiaxi Wang; Donggang Xu
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 297 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0141-5492
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
An extract of bovine hypothalamus is known to be mitogenic for human keratinocytes in vitro. In order to identify the responsible substance(s), biochemical characterization and subsequent bioassay of the extract in a serum-free culture system were performed. The keratinocyte growth-promoting activit
Human keratinocyte growth factor (KGF) is an epithelial cell specific mitogen which is secreted by normal stromal fibroblasts. In the present studies, we demonstrate that KGF is as potent as EGF in stimulating proliferation of primary or secondary human keratinocytes in tissue culture. Exposure of K
We have previously described the mitogenic and wound-healing properties of keratinocyte-conditioned medium (KCM). In this study we investigated the eect of KCM on the activation of second messenger systems and the expression of proto-oncogene in cultured human skin ยฎbroblasts. We also present a part
Estrogen is thought to be an important etiologic agent in endometrial and breast cancers. However, the mechanism or mechanisms by which estrogen acts as a hormonal carcinogen are not well understood. We hypothesize that in response to chronic exposure to estrogens, human endometrial stromal fibrobla