✦ LIBER ✦

Constrained amino acids. An approach to the synthesis of 3-substituted prolines

✍ Scribed by Philip P. Waid; Gary A. Flynn; Edward W. Huber; Jeffrey S. Sabol

Publisher: Elsevier Science
Year: 1996
Tongue: French
Weight: 164 KB
Volume: 37
Category: Article
ISSN: 0040-4039
DOI: 10.1016/0040-4039(96)00775-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Asymmetric Synthesi

ChemInform Abstract: Asymmetric Synthesis of 4-Substituted Prolines as Conformationally Constrained Amino Acid Analogues.

✍ Qian Wang; N. Andre Sasaki; Pierre Potier 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

ChemInform Abstract: An Asymmetric Synth

ChemInform Abstract: An Asymmetric Synthesis Protocol to Prepare Topographically Constrained β-Substituted Aromatic Amino Acids

✍ Subo Liao; Victor J. Hruby 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

Solid-phase amino-zinc-enolate cyclizati

Solid-phase amino-zinc-enolate cyclization for the synthesis of 3-substituted prolines

✍ Philippe Karoyan; Antonio Triolo; Rossano Nannicini; Danilo Giannotti; Maria Alt 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 214 KB

Preparation of 3-substituted prolines was achieved by extension to Solid Phase Organic Synthesis (SPOS) of the amino-zinc-enolate cyclization we have recently described. I Functionalizations of proline at C-3 were considered by nucleophilic substitutions of an iodo derivative obtained on the resin.

A new approach to the stereoselective sy

A new approach to the stereoselective synthesis of conveniently protected α-allyl substituted amino acids; chiral key compounds in the synthesis of constrained peptide isostere constituents

✍ Ramón Badorrey; Carlos Cativiela; Maria D. Díaz-de-Villegas; JoséA. Gálvez; Yola 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 448 KB

Enantiomerically pure ot-allyl-N-Boc-aminoamides were prepared by Curtius rearrangement of tx,ct-dialkyl chiral 2-cyanoesters obtained by the diastereoselective allylation of chiral 2-cyanoesters according to a modification of our previously described procedure.

Nucleophilic substitution of protected 2

Nucleophilic substitution of protected 2-amino-4-butanoic acid. An easy route to exotic amino acids and conformationally constrained peptides

✍ Paola Ciapetti; André Mann; Angèle Shoenfelder; Maurizio Taddei 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 211 KB

The synthesis of a series of novel (t-amino acids based on the nucleophilic substitution of protected 2-amino-4-bromobutanoic acid (1) is described. Basic, acidic or neutral amino acids can be obtained; chimerical amino acids carrying a coenzyme type structure in the side chain, multifunctional amin

A New Approach to the Synthesis of β-Ami

A New Approach to the Synthesis of β-Amino Acids.

✍ Claudia Della Rosa; Salvador Gil; Pablo Rodriguez; Margarita Parra 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views