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Constitutive tyrosine and serine phosphorylation of STAT4 in T-cells transformed with HTLV-I

โœ Scribed by Takehiro Higashi; Junichi Tsukada; Yasuhiro Yoshida; Takamitsu Mizobe; Fumihiko Mouri; Yasuhiro Minami; Hiroaki Morimoto; Yoshiya Tanaka


Book ID
108731815
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
267 KB
Volume
10
Category
Article
ISSN
1356-9597

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We and others have reported an association between raf-1 protein serine/threonine kinase activity and transformation of mammalian cells. Because constitutive tyrosine phosphorylation of specific polypeptides is, in general, indicative of the transformed state of cells, we investigated the effect of