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Constitutive Activation of the Neuregulin-1/erbB Signaling Pathway Promotes the Proliferation of a Human Peripheral Neuroepithelioma Cell Line

✍ Scribed by Kenneth B. Fallon; Necat Havlioglu; Leo H. Hamilton; Tammy P.H. Cheng; Steven L. Carroll


Book ID
111601822
Publisher
Springer US
Year
2004
Tongue
English
Weight
116 KB
Volume
66
Category
Article
ISSN
0167-594X

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Constitutive activation of the neureguli
✍ Paul W. Frohnert; Mark S. Stonecypher; Steven L. Carroll πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 385 KB πŸ‘ 1 views

## Abstract Neuregulin‐1 (NRG‐1) proteins promote Schwann cell survival, differentiation and proliferation during development. High levels of an NRG‐like activity are also present in some human peripheral nerve sheath tumors, suggesting that NRG‐1 isoforms may be involved in the development of thes