Constant time imaging approaches to NMR microscopy

✍ Scribed by Sungmin Choi; Xiao-Wu Tang; D. G. Cory

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 464 KB
• Volume: 8
• Category: Article
• ISSN: 0899-9457
• DOI: 10.1002/(sici)1098-1098(1997)8:3<263::aid-ima4>3.0.co;2-8

✦ Synopsis

The resolution in nuclear magnetic resonance (NMR) be included in the design of the experiment. The goal of the microscopy is limited by a combination of the inherent low sensitivity project was to develop a system that is useful for biomedical of NMR, the destruction of spin magnetization gratings by molecular applications to excised tissue or small biological samples. This diffusion, and variations in the local magnetic field strength introduced perspective leads to a set of desirable characteristics, that were by spatial variations of the bulk susceptibility. While none of these prioritized as thus: may be completely overcome, constant time imaging methods are the optimal approach to recording images when the above factors 1. Obtain the highest possible resolution (the goal is 2 1 are important. This method aims to instantaneously create a spin magnetization grating and then to efficiently sample the spatially in-2 1 8 mm 3 ), variant portion of this-corresponding to a selected Fourier compo-2. Obtain an image that is substantially free of artifacts and nent of the sample distribution. The method is introduced, analyzed distortions, in the presence of molecular diffusion, and demonstrated to yield 3. Preserve all means of building in contrast, and high-resolution images. To implement the method, a microscopy 4. Keep the time required to acquire an image as low as probe was constructed for a standard-bore 400-MHz NMR spectrompossible.