Consolidation therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of cytosine arabinoside, epipodophyllotoxins and cyclophosphamide
β Scribed by E.J. Estlin; S.M. Yule; S.P. Lowis
- Book ID
- 117817316
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 193 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0305-7372
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## Abstract In a comparison of treatments for standardβrisk acute lymphoblastic leukaemia in children (UKALL III), there were no differences in remission lengths between regimens with or without secondβline drugs (cytosine arabinoside and asparaginase) and with continuous or discontinuous mercaptop
One hundred six children with newly diagnosed non-T-, non-B-cell acute lymphoblastic leukemia (ALL) were treated in a Pediatric Oncology Group (POG) pilot study in which six courses of intermediate-dose methotrexate (MTX) and cytosine arabinoside (Ara-C) (1 g/m2 each) were added to a "backbone" of s