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Cytosine arabinoside/cyclophosphamide pulses during continuation therapy for childhood acute lymphoblastic leukemia. Potential selective effect in T-cell leukemia

✍ Scribed by Stephen J. Lauer; Donald Pinkel; George R. Buchanan; Peggy Sartain; Joann M. Cornet; Robert Krance; Luis D. Borella; James T. Casper; Larry E. Kun; Raymond G. Hoffman; Bruce M. Camitta


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
509 KB
Volume
60
Category
Article
ISSN
0008-543X

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One hundred six children with newly diagnosed non-T-, non-B-cell acute lymphoblastic leukemia (ALL) were treated in a Pediatric Oncology Group (POG) pilot study in which six courses of intermediate-dose methotrexate (MTX) and cytosine arabinoside (Ara-C) (1 g/m2 each) were added to a "backbone" of s