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Connective tissue growth factor increases matrix metalloproteinase-2 and suppresses tissue inhibitor of matrix metalloproteinase-2 production by cultured renal interstitial fibroblasts

โœ Scribed by Min Yang; Haichang Huang; Jingzi Li; Wen Huang; Haiyan Wang


Book ID
109080481
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
225 KB
Volume
15
Category
Article
ISSN
1067-1927

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## Abstract Fibroblasts, a major constituent of gingival connective tissue, can produce immunoregulatory cytokines and proteolytic enzymes that may contribute to tissue destruction. In this study, we evaluated the production of matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMPs), an