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Conjugation with Cationic Cell-Penetrating Peptide Increases Pulmonary Absorption of Insulin

โœ Scribed by Patel, Leena N.; Wang, Jeffrey; Kim, Kwang-Jin; Borok, Zea; Crandall, Edward D.; Shen, Wei-Chiang

Book ID
111919424
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
988 KB
Volume
6
Category
Article
ISSN
1543-8384

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## Abstract To improve the efficiency of intracellular delivery of photosensitizers and the efficacy of photodynamic therapy, a membraneโ€penetrating arginine oligopeptide (R~7~) was conjugated to 5โ€[4โ€carboxyphenyl]โ€10,15,20โ€triphenylโ€2,3โ€dihydroxychlorin (TPC). The resulting conjugate (R~7~โ€“TPC) e