𝔖 Bobbio Scriptorium
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Conjugates between monoclonal antibodies to HBsAg and cytosine arabinoside

✍ Scribed by Shouval, Daniel; Adler, Ruth; Wands, Jack R.; Hurwitz, Esther


Book ID
123455806
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
622 KB
Volume
3
Category
Article
ISSN
0168-8278

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The therapeutic effectiveness of xenogeneic monoclonal antibodies (MAbs) (xIg) or their conjugates with toxins (xIg-Tx) is undermined because of their inherent immunogenicity. This complication may be overcome by converting the antigenic xIg to tolerogenic derivatives by coupling an appropriate numb