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Conjugate addition of amines to (Rs)-10-isobornyl vinyl sulfoxides

โœ Scribed by Stephen G. Pyne; Peter Bloem; Renate Griffith


Book ID
104204642
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
574 KB
Volume
45
Category
Article
ISSN
0040-4020

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Conjugate addition of amines to vinyl su
โœ Heather Tye ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 105 KB

The synthesis of a range of b-amino sulfoximide derivatives is described. The conjugate addition of simple amines or amino acids to N-tosyl phenyl vinyl sulfoximide was achieved in moderate to good yield (41-95%). Electron poor nucleophiles such as tosyl amide or benzyl carbamate were found to be un