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Conformationally Rigid Chiral Bicyclic Skeleton-Tethered Bipyridine N,N′- Dioxide as Organocatalyst: Asymmetric Ring Opening of meso -Epoxides

✍ Scribed by Gnanamani, Elumalai; Someshwar, Nagamalla; Sanjeevi, Jayakumar; Ramanathan, Chinnasamy Ramaraj


Book ID
124074789
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
366 KB
Volume
356
Category
Article
ISSN
1615-4150

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Enantioselective ring opening of meso-ep
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An enantioselective ring opening of meso-epoxides with tetrachlorosilane in the presence of diisopropylethylamine exploiting chiral bipyridine N,N%-dioxides as catalysts affords the corresponding chlorohydrins in high enantioselectivities of up to 90% ee.