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Conformationally restricted analogs of deoxynegamycin

✍ Scribed by B. Raju; Sampathkumar Anandan; Shihai Gu; Prudencio Herradura; Hardwin O’Dowd; Bum Kim; Marcela Gomez; Corinne Hackbarth; Charlotte Wu; Wen Wang; Zhengyu Yuan; Richard White; Joaquim Trias; Dinesh V. Patel

Book ID
108073328
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
282 KB
Volume
14
Category
Article
ISSN
0960-894X

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The synthesis of the five-membered cyclic phosphorodiamidic-acid derivatives 10 and 11 as well as the preparation of the six-membered cyclic phosphates 18, 19,22-25, and phosphoramidates 27-32 is described. The effects of these conformationally restricted platelet-activating factor analogs on rabbit