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Conformationally Constrained Analogues of Diacylglycerol. 19. Synthesis and Protein Kinase C Binding Affinity of Diacylglycerol Lactones Bearing an N -Hydroxylamide Side Chain

โœ Scribed by Choi, Yongseok; Kang, Ji-Hye; Lewin, Nancy E.; Blumberg, Peter M.; Lee, Jeewoo; Marquez, Victor E.

Book ID
126088538
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
67 KB
Volume
46
Category
Article
ISSN
0022-2623

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Conformationally Constrained Analogues o
Conformationally Constrained Analogues of Diacylglycerol. 18. The Incorporation of a Hydroxamate Moiety into Diacylglycerol-Lactones Reduces Lipophilicity and Helps Discriminate between sn-1 and sn-2 Binding Modes to Protein Kinase C (PK-C). Implications for Isozyme Specificity.
โœ Lee, Jeewoo; Han, Kee-Chung; Kang, Ji-Hye; Pearce, Larry L.; Lewin, Nancy E.; Ya ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 11 KB