𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7

✍ Scribed by Johnson Agniswamy; Bin Fang; Irene T. Weber


Publisher
Springer
Year
2009
Tongue
English
Weight
630 KB
Volume
14
Category
Article
ISSN
1360-8185

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Conformational restrictions in the activ
✍ Chao-Zhou Ni; Chenglong Li; Joe C. Wu; Alfred P. Spada; Kathryn R. Ely πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 488 KB

## Abstract Caspases are cysteine proteases that play a critical role in the initiation and regulation of apoptosis. These enzymes act in a cascade to promote cell death through proteolytic cleavage of intracellular proteins. Since activation of apoptosis is implicated in human diseases such as can

Expression of mitochondrial Apo2.7 molec
✍ A. BΓΌssing; W. Vervecken; M. Wagner; B. Wagner; U. PfΓΌller; M. Schietzel πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 285 KB πŸ‘ 1 views

Background: It is unclear whether expression of newly described mitochondrial Apo2.7 molecules (7A6 antigen) is specific for apoptosis or may also occur in necrosis. Methods: We incubated human lymphocytes with the apoptosis-inducing mistletoe lectin (ML) I and the cell membrane-permeabilizing visco

Regulation of the proapoptotic activity
✍ Jae Eun Kang; Shin Ae Choi; Jung Bum Park; Kwang Chul Chung πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 435 KB

Dual specific protein kinase Dyrks are thought to play a key role in the regulation of cell growth in a variety of cellular systems. Interestingly, human Dyrk1 is mapped to the Down's syndrome (DS) critical region on chromosome 21, and thought to be a candidate gene responsible for the mental retard