## Abstract Although neurons of the PNS no longer require neurotrophins such as Nerve Growth Factor (NGF) for their survival, such factors are involved in regulating axonal sprouting and regeneration after injury. In addition to the neurotrophin receptors, sensory neurons are reported to express IG
✦ LIBER ✦
Insulin-Like Growth Factor-1 and Insulin Inhibit Caspase-3/7 Activation Initiated by Interleukin-1β in the Rat Eye Retinal Neurons
✍ Scribed by S. S. Shushanov
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 378 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0007-4888
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Swiss 3T3 mouse fibroblasts were exposed to 10 microM colchicine to disrupt microtubules, then stimulated with insulin-like growth factor-I. Immunoprecipitation experiments showed that insulin-like growth factor-I receptor and insulin receptor substrate-1 were tyrosine phosphorylated to the same ext