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Conformational restriction of peptidyl immunogens with covalent replacements for the hydrogen bond

โœ Scribed by Arnold C. Satterthwait; Thomas Arrhenius; Robert A. Hagopian; Fidel Zavala; Victor Nussenzweig; Richard A. Lerner


Book ID
119528920
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
532 KB
Volume
6
Category
Article
ISSN
0264-410X

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The X-ray crystal structures of the complexes C6H5CHOoBF31 and H2C=C(CH3)CHO.BF32 reveal that the BF3 is coordinated to the oxygen lone pair which is syn to the formyl proton and, further, that the formyl proton and one B-F bond are in plane (eclipsed) with respect to the C-O-B triad, as shown in 1.