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Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogs

✍ Scribed by Epifani, E.; Lapucci, A.; Macchia, B.; Macchia, F.; Tognetti, P.; Breschi, M. C.; Del Tacca, M.; Martinotti, E.; Giovannini, L.


Book ID
120928203
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
900 KB
Volume
26
Category
Article
ISSN
0022-2623

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Experiments on the Total Synthesis of Ly
✍ Rudolf O. Duthaler; Peter Mathies; Walter Petter; Christoph Heuberger; Veronica πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 German βš– 265 KB

## Abstract The substituted 1,2,3,4,4a,9,10,10a‐octahydrophenanthrene‐4,9‐dione **2**, synthesized from the cyclohexanone **8** and quinone __11__ (__Scheme 2__), was found by X‐ray analysis adn ^1^H‐NMR studies to be the isomer with __cis__‐junction of the saturated rings. The __cis__‐fusion could