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Conformational-dependent recognition of influenza virus hemagglutinin by murine T helper clones

โœ Scribed by Kingston H. G. Mills; John J. Skehel; D. Brian Thomas


Book ID
102826373
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
513 KB
Volume
16
Category
Article
ISSN
0014-2980

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A negative selection procedure has been developed to obtain murine T helper clones specific for variable regions of the influenza A hemagglutinin. T cell lines, established from mice primed by intranasal infection with X31 (H3N2) virus, were cross-stimulated with natural variant viruses of known pri