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Conformational constraints in protein degradation by the 20S proteasome

✍ Scribed by Wenzel, Thorsten ;Baumeister, Wolfgang

Book ID
109964627
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
582 KB
Volume
2
Category
Article
ISSN
1545-9993

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## Abstract The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin‐dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. Alternatively, certain p