𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conformational changes of polypeptides on crystallization

✍ Scribed by H. Brumberger; B. Cheng

Publisher
Wiley (John Wiley & Sons)
Year
1974
Tongue
English
Weight
136 KB
Volume
13
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

We are interested in determining whether polypeptides retain their conformation on crystallizing from various solvent systems.'-3 We give here a brief summary of some systematic infrared measurements on a series of five polypeptides. The spectra of solutions of the polypeptides in pure trifluoroacetic acid, (trifluoroacetic acid-TFA, cis-l,2-dichloroethylene-DCE, poly-L-alanine-PLA, poly-Lleucine-PLL, poly-ybenxyl-L-glutamate-PBLG, poly-L-valine-PLV, poly-y-methyl-L-glutamate-P31LG), and in a mixed solvent (trifluoroacetic acid plus dichloroethylene) were obtained, as

πŸ“œ SIMILAR VOLUMES

Conformational changes of polypeptides i
Conformational changes of polypeptides in intense electric fields
✍ C. P. Bean; A. J. Bennett πŸ“‚ Article πŸ“… 1973 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 380 KB

## Abstract Employing a simple β€œall or none” statistical theory, a calculation is given of the phase diagram in electric field–temperature space for the helix–coil transition of a polypeptide with nonpolar residues but charged end groups. The principal results are (i) the transition field extrapola

Conformational studies on the pyridoxal
Conformational studies on the pyridoxal Schiff bases of polypeptides
✍ M. Dentini; G. Perretti; M. Savino; P. De Santis; A. S. Verdini πŸ“‚ Article πŸ“… 1978 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 520 KB

The pyridoxal Schiff bases of the polypeptides poly(L-lysine), poly(L-ornithine), and poly(L-a,y-diaminobutyric acid) were prepared and investigated in water/methanol by CD spectra and equilibrium dialysis experiments. Only the poly(L-a,?-diaminobutyric acid) derivative is characterized by a relevan

Changes in polypeptide conformer populat
Changes in polypeptide conformer populations induced by the solvent environment
✍ F. Xu; T. A. Cross πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 234 KB πŸ‘ 2 views

Changes in the solvent dielectric properties are correlated with changes in polypeptide conformer populations. Gramicidin A, a peptide native to membrane environments, forms a variety of well deÐned dimeric conformations in relatively low dielectric organic solvents. However, changes in this environ

New optimization method for conformation
New optimization method for conformational energy calculations on polypeptides: Conformational space annealing
✍ Lee, Jooyoung (author);Scheraga, Harold A. (author);Rackovsky, S. (author) πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons Inc. 🌐 English βš– 199 KB πŸ‘ 2 views

A new optimization method is presented to search for the global minimum-energy conformations of polypeptides. The method combines essential aspects of the build-up procedure and the genetic algorithm, and it introduces the important concept of ''conformational space annealing.'' Instead of consideri