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Conformational change of poly(l-lysine) induced by lipid vesicles of dilauroylphosphatidic acid

โœ Scribed by Kohsuke Fukushima; Yoshihiro Muraoka; Tohru Inoue; Ryosuke Shimozawa


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
673 KB
Volume
30
Category
Article
ISSN
0301-4622

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Poly-L-lysine exists as an a-helix at high pH and a random coil at neutral pH. When the a-helix is heated above 27ะŠC, the macromolecule undergoes a conformational transition to a b-sheet. In this study, the stability of the secondary structure of poly-L-lysine in solutions subjected to shear flow, a

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## Abstract The conformational changes of polyโ€__N__^ฮต^โ€glutarylโ€Lโ€lysine (PGL) and polyโ€__N__^ฮต^โ€succinylโ€Lโ€lysine (PSL) in various salt solutions were studied by use of ORD and potentiometric titration measurements. The addition of alkali metal salts to the fully ionized PGL or PSL solution cause