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Conformational and molecular study of the 4-(2-carboxyethyl)-1,2,3,4-tetrahydrocyclopent[b]indole

โœ Scribed by J.G. Rodriguez; F. Temprano; C. Esteban-Calderon; M. Martinez-Ripoll; S. Garcia-Blanco


Book ID
108372648
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
554 KB
Volume
41
Category
Article
ISSN
0040-4020

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A series of irrfino 1,2,3,4-tetrahydrocyclopent [b]indole caltmn~tes was prepared and evaluated as dual acetyichollm, stem~ (ACHE) and monoan-fine oxida~ (MAO) inhibitors. Halogen substitution ortho to the cartmn-me functionality in the eight position resulted in a significant increase in binding af