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Conformational Analysis of TMC114, a Novel HIV-1 Protease Inhibitor

โœ Scribed by Nivesanond, Kanda; Peeters, Anik; Lamoen, Dirk; Van Alsenoy, Christian


Book ID
125931040
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
561 KB
Volume
48
Category
Article
ISSN
0095-2338

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The design and synthesis of potential steroidal HIV-1 protease inhibitors is described. Compounds derived from 11-amino-12-keto-cholanic acid derivatives show modest activity.