Conformational analysis of nucleic acids Extended Hückel study on the D-ribose (C3, -exo)-phosphate unit
✍ Scribed by Dane Vasilescu; Francine Camous; Jean-Noël Lespinasse
- Book ID
- 115902610
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 296 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
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## Abstract The extended Hückel theory (EHT) was used as a quantum mechanical approach for the determination of the best conformation of cyclic AMP. Both geometrical and quantum mechanical studies were necessary to ascertain the configuration of the sugar ring and phosphate ring. This was due to th
## Abstract The conformation of the ribose‐phosphate unit for the four principal configurations of the sugar ring has been studied using the extended Hückel theory and the Lennard–Jones empirical potential. Initially, the oxygen atoms of the p3 and p5 groups were not taken into account. With this r