๐”– Bobbio Scriptorium
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Conformational Analysis of Cyclolinopeptides A and B.

โœ Scribed by Teruki Matsumoto; Akira Shishido; Hiroshi Morita; Hideji Itokawa; Koichi Takeya


Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
33
Category
Article
ISSN
0931-7597

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Cyclolinopeptide A, a cyclic nonapeptide, was isolated in 1956 from linseed oil.' In 1966 Prox and Weygand' determined the amino acid composition and they elucidated the sequence of the peptide, demonstrating the following chemical structure: \*Dedicated to the memory of Professor F. Weygand.

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## SYNOPSIS CD and nmr techniques have been used to study, in acetonitrile solution, the ion-complexing capability of cyclolinopeptide A (CLA) , a cyclic nonapeptide of sequence cyclo-( Pro-Pro-Phe-Phe-Leu-Ile-Ile-Leu-Val) endowed with remarkable cytoprotective ability in vitro, and the conformati

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