𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conformational analysis of a synthetic carboxylic ionophore in solution by 1H NMR spectroscopy

✍ Scribed by Hitoshi Kuboniwa; Kazuo Yamaguchi; Akira Hirao; Seiichi Nakahama; Noboru Yamazaki

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
428 KB
Volume
24
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

The ' H NMR spectra of the potassium salt of a synthetic polyether carboxylic ionophore, HO[CH,CH,0(1,2-C&)O],CH,(1,2-C6&)COOH (l), in CDCI, were assigned by two-dimensional NMR methods (2D chemical shift correlation and 2D NOE). The gauche conformer about the C-C bond of the 1,2-dioxyethylene groups of the potassium salt of 1 were found to be predominant from the analysis of the proton-proton vicinal coupling constants. Based on rotamer population analysis, together with nuclear Overhauser effect data, the preferred conformation of the potassium salt of 1 in the solution was estimated.

πŸ“œ SIMILAR VOLUMES

Conformational features of imipramine hy
Conformational features of imipramine hydrochloride in aqueous solution as detected by 1H NMR relaxation analysis
✍ Elena Gaggelli; Nadia Marchettini; Gianni Valensin πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 312 KB

## Abstract Proton NMR measurements were performed and ^1^Hο£Ώ^1^H dipolar interaction energies were measured to delineate the conformation of imipramine in solution. Self‐association of imipramine into dimers was observed and a dimerization constant of 121 mol^βˆ’1^ was calculated. The motional correl

Application of 1H NMR bi-selective relax
Application of 1H NMR bi-selective relaxation times to conformational analysis in solution
✍ Makiko Sugiura; Narao Takao; Hideaki Fujiwara πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 483 KB

The usefulness of 'H bi-selective relaxation times ( 2 ' : ' ) and selective relaxation times (T,') for structure and conformation determination is emphasized. A pulse sequence has been devised which provides the apparent observed T : ' . The cross-relaxations (q,) or Fi, values are derived from the

Conformational analysis of the tropane a
Conformational analysis of the tropane analogue of pethidine and related compounds by 1H NMR spectroscopy
✍ A. F. Casy; J. E. Coates πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 English βš– 426 KB

## Abstract The preferred solute conformation of ethyl 3α‐phenyltropane‐3β‐carboxylate hydrochloride, the tropane analogue of pethidine, is shown to be a piperidine chair with an axial 3‐phenyl substituent by analysis of its ^1^H NMR characteristics and spectral comparisons with model compounds. Co