Conformation of Vinblastine in Aqueous Solution Determined by 2D 1 H- and 13 C-nmr Spectroscopy
β Scribed by Gaggelli, Elena; Valensin, Gianni; Stolowich, Neal J.; Williams, Howard J.; Scott, A. Ian
- Book ID
- 127084739
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 358 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0163-3864
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The conformation and dynamic stucture of single-stranded poly(inosinic acid), poly(I), in aqueous solution a t neutral pH have been investigated by nmr of four nuclei a t different, trequencies: 'H (90 and 250 MHz), 'H (13.8 MHz), '"C (75.4 MHz), and 31P (36.4 and 111.6 MHz). Measurements of the pro
## Abstract The 270 MHz ^1^H and 22.6 MHz ^13^C NMR spectra of DLβphosphothreonine in D~2~O have been measured and analysed as a function of pD. The __trans__β__trans__ conformation of the fragment HβΞ±ο£ΏCβΞ±ο£ΏCβΞ²ο£ΏOο£ΏP predominates at all pD values. The CβΞ²βO __gauche__ contribution is notably larger fo