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Conformation of the C-Terminal Domain of the Pro-Apoptotic Protein Bax and Mutants and Its Interaction with Membranes †

✍ Scribed by del Mar Martínez-Senac, María; Corbalán-García, Senena; Gómez-Fernández, Juan C.

Book ID
127384430
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
103 KB
Volume
40
Category
Article
ISSN
0006-2960

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## Abstract Bax, a multi‐domain protein belonging to the large family of Bcl‐2 proteins, has a pivotal role for the initiation of the cytochrome __c__‐mediated apoptosis, a vital physiologic process to eliminate damaged or unwanted cells. In response to specific stimuli Bax translocates from cytoso