The conformation of two highly potent parathyroid hormone (PTH) antagonists was investigated in water/2,2,2-trifluoroethanol mixtures. The two peptides are derived9om the sequence and have a D -T v ~ replacing Gly in position 12. In the analogue derivedfrom PTHrP, Lys" was replaced by Leu to remove
Conformation of CD4-derived cyclic hexapeptides by nmr and molecular dynamics
β Scribed by Sougen Ma; Malcolm J. McGregor; Fred E. Cohen; Peter V. Pallai
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1994
- Tongue
- English
- Weight
- 969 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The conformation of diribosylribitol phosphate was studied by means of NMR spectroscopy and molecular dynamics (MD). Starting from 3 J( 1 H, 1 H), 3 J( 31 P, 1 H) and 3 J( 31 P, 13 C) couplings, measured from 1 H NMR, 13 C NMR and COSY spectra, the conformations of the ribose residues and the phosph
The conformation of [Val4, Ile7]Angiotensin III has been studied in aqueous and micellar (DPC) media by 2D NMR and MD simulations. Complete resonance assignments have been made using combination of DQF-COSY, TOCSY and ROESY/NOESY spectra. The NMR parameters coupling constants, deuterium [ 3J NH exch