1998 structure structure (organic substances) K 9000 ## 13 -035 Conformational Distribution of the Potentially Neurotoxic Metabolite of Haloperidol, HPP + , by NMR Spectroscopy, X-Ray Crystallography, and Molecular Dynamics Simulations. -The chlorophenyl and pyridinium rings of neurotoxic pyridin
Conformation Analysis of Aspartame-Based Sweeteners by NMR Spectroscopy, Molecular Dynamics Simulations, and X-ray Diffraction Studies
β Scribed by Antonia De Capua; Murray Goodman; Yusuke Amino; Michele Saviano; Ettore Benedetti
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 418 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1439-4227
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A dipeptide taste ligand L-aspartyl-D-2-aminobutyric acid-(S)-alpha-ethylbenzylamide was found to be about 2000 times more potent than sucrose. To investigate the molecular basis of its potent sweet taste, we carried out conformational analysis of this molecular and several related analogues by NMR
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