Confirmation of in situ exposure of fish to secondary treated bleached-kraft mill effluent using a laboratory simulation

Quantitation of dose-dependent increases

Quantitation of dose-dependent increases in CYP1A1 messenger RNA levels in juvenile chinook salmon exposed to treated bleached-kraft mill effluent using two field sampling techniques

✍ Pamela M. Campbell; George M. Kruzynski; Ian K. Birtwell; Robert H. Devlin 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB

## Abstract Increases in hepatic CYP1A1 messenger RNA (mRNA) levels were quantitated, using a reverse‐transcriptase–competitive‐polymerase‐chain‐reaction assay, from juvenile chinook salmon following exposure to treated bleached‐kraft mill effluent (BKME). Two tissue preservation techniques, alcoho