Configuration of Alicyclic Amino-Alcohols
✍ Scribed by FODOR, G.; KISS, J.
- Book ID
- 109561700
- Publisher
- Nature Publishing Group
- Year
- 1949
- Tongue
- English
- Weight
- 191 KB
- Volume
- 164
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/164917a0
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📜 SIMILAR VOLUMES
## Abstract magnified image Alicyclic __N__‐substituted 1,3‐amino alcohols **13‐18** were prepared in a facile way in a one‐pot procedure from 1,3‐oxazines **5‐8** in the presence of a ketone **9‐12**. The complex reaction involves palladium‐catalyzed reduction, debenzylation and/or transimination
A large set of syn-and anti-1,2-amino alcohols has been synthesized. Upon comparison of the CH 6 O and CH 6 N 1 H NMR shifts a general trend has been observed, making it possible to determine the relative configuration of 1,2-amino alcohols without derivatization or shift reagents.