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Cone Photoreceptors Develop Normally in the Absence of Functional Rod Photoreceptors in a Transgenic Swine Model of Retinitis Pigmentosa

✍ Scribed by Fernandez de Castro, Juan P.; Scott, Patrick A.; Fransen, James W.; Demas, James; DeMarco, Paul J.; Kaplan, Henry J.; McCall, Maureen A.

Book ID
125857008
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Year
2014
Weight
1003 KB
Volume
55
Category
Article
ISSN
1552-5783

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Transgenic mice expressing a dominant mutation in the gene for the phototransduction molecule rhodopsin undergo retinal degeneration similar to that experienced by patients with the retinal degenerative disease, retinitis pigmentosa (RP). Although the mutation is thought to cause photoreceptor degen