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Conduction block in neuropathies with necrotizing vasculitis

✍ Scribed by Angèle Ropert; Dr. Stéphane Metral

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
334 KB
Volume
13
Category
Article
ISSN
0148-639X

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✦ Synopsis

Abstract

Thirty‐two patients with a mononeuropathy multiplex associated with a systemic necrotizing vasculitis were studied. The main abnormality was a loss of motor and sensory axons confirmed by electrophysiological and histological methods. A conduction block was observed in five patients, but only one was at a usual site of compression. Based on previous pathological studies and the experimental data in human and animals, the mechanism of the block is proposed to be ischemic. It is suggested that a conduction block in one nerve in a neuropathy with two or more individual nerves affected and with electrophysiological features of axonal degeneration may be due to a vasculitis.

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