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Conditions of radioiodination with iodogen as oxidizing agent

โœ Scribed by Saha, Gopal B.; Whitten, Julie; Go, Raymundo T.

Book ID
123446928
Publisher
Elsevier Science
Year
1989
Weight
320 KB
Volume
16
Category
Article
ISSN
0883-2897

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โœ H.J. Sinn; H.H. Schrenk; E.A. Friedrich; D.P. Via; H.A. Dresel ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 539 KB

In an attempt to improve conditions for radioiodination of sensitive proteins we used N-bromosuccinimide as a mild oxidizing agent. Under gentle conditions we increased the average labeling efficiency of a wide variety of proteins to above 97%. There was no loss of binding activity of low density li