Conditions for detecting overlapped peaks with principal component analysis in hyphenated chromatographic methods
β Scribed by Gemperline, Paul J.; Hamilton, J. Craig.
- Book ID
- 118252940
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 518 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0003-2700
No coin nor oath required. For personal study only.
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Evolvmg factor analysis and related techmques are pronuamg methods for peak punty control m hqmd chromatography mth photodmde-array detection (DAD) Practical apphcatlon of these techmques, however, can be hnuted by Instrumental and expenmental non-ldeahtles Possible reasons Include a non-zero or slo
The performance of the heurlstlc evolvmg latent proJectIons (HELP) method 1s mvestlgated for peak purity control m hqmd chromatography Hrlth photodlode array detectlon HELP and evolvmg factor analysis performed equally well, both techmques could detect less than 1% of a spectrally slmdar lmpunty eve