Condensation products of 2-bromo-3-substituted-inden-1-ones with several primary amines
β Scribed by Seiko Nan'ya; Takeo Kitahara; Kenichi Fujii; Ashok C. Bajji; Yasuo Butsugan
- Book ID
- 112130471
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1992
- Tongue
- English
- Weight
- 246 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-152X
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## Abstract Isoquinolinones were brominated using __N__βbromosuccinimide in dimethylformamide at room temperature to give 4βbromoβ3βsubstituted isoquinolinβ1β(2__H__)βones. The reaction of these isoquinolinones with propargyl bromide in the presence of anhydrous potassium carbonate yielded __N__ an
A/~trac~ A new type of anionic Β’yelization has been discovered in which the condensation of alkyl benzoates with simple nitriles, induced by an excess of LDA, leads directly to substituted-3-amino-2-indan-l-ones. The corresponding intermediL.t,~-[~-oxmitriles undergo cyclization to give, in most ins