Some years ago I-3 we described a new reaction, the condensation of the vinylcyclenole ( 1) and ( 2) with the cyclic 1,3-diketones (3) and ( 4) widely used by us and by others in the total synthesis of estrone, D-homo-estrone and their analogs2-g . However the scope and limits of application of the
Condensation of isatin with diketones
✍ Scribed by Gj. Stefanović; M. Pavičić-Woss; Lj. Lorenc; M.Lj. Mihailović
- Publisher
- Elsevier Science
- Year
- 1959
- Tongue
- French
- Weight
- 555 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0040-4020
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## Abstract By condensing the potassium salt of isatinic acid ‐ (__o__‐aminophenyl)‐glyoxylic acid ‐ with urea, __N__‐substituted ureas and ethyl carbamate, 2‐hydroxyquinazoline‐4‐carboxylic acid was obtained, in excellent yield. In a similar condensation with guanidine, potassium isatinate reacted
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