𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Condensations of isatinic acid with ureas, ethyl carbamate and guanidine

✍ Scribed by Gj. Stefanović; Lj. Lorenc; M. Lj. Mihailović

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
545 KB
Volume
80
Category
Article
ISSN
0165-0513

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

By condensing the potassium salt of isatinic acid ‐ (o‐aminophenyl)‐glyoxylic acid ‐ with urea, N‐substituted ureas and ethyl carbamate, 2‐hydroxyquinazoline‐4‐carboxylic acid was obtained, in excellent yield. In a similar condensation with guanidine, potassium isatinate reacted quantitatively to give 2‐aminoquinazoline‐4‐carboxylic acid. Various derivatives were obtained from these new acids by methylation and decarboxylation reactions.

📜 SIMILAR VOLUMES

Orthoamides. Part 65. Condensation React
Orthoamides. Part 65. Condensation Reactions of Amidines, Guanidines, Hydrazine and Hydrazine Derivatives with Orthoamides of Alkyne Carboxylic Acids.
✍ Willi Kantlehner; Jochen Mezger; Ruediger Stieglitz; Kai Edelmann; Hansjoerg Leh 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 43 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.