Condensation of glyoxal with triethylenetetraamine. Stereochemistry, cyclization and deprotection

✍ Scribed by Gwénaëlle Hervé; Hélène Bernard; Nathalie Le Bris; Michel Le Baccon; Jean-Jacques Yaouanc; Henri Handel

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 203 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00260-9

✦ Synopsis

A mixture of bis-aminal isomers was obtained from aqueous glyoxal-triethylenetetraamine condensation. The irreversible isomerization of the species was observed and a new synthesis of cyclen proposed.