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Condensation of collagen fibrils in the direct vicinity of fibroblasts as a cause of gel contraction

✍ Scribed by Yamato, Masayuki; Adachi, Eijiro; Yamamoto, Kiyotaka; Hayashi, Toshihiko

Book ID
123204383
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
87 KB
Volume
14
Category
Article
ISSN
0945-053X

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Mixing feed fibroblasts with soluble collagen and serum-supplemented culture medium at 37 degrees C results in the entrapment of cells within the polymerizing collagen matrix. This cellular-collagen complex is referred to as a fibroblast-populated collagen lattice (FPCL). In time, this FPCL undergoe