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Complementary roles of microtubules and microfilaments in the lung fibroblast-mediated contraction of collagen gels: Dynamics and the influence of cell density

✍ Scribed by Robert A. Redden; Edward J. Doolin


Book ID
119987413
Publisher
Society for In Vitro Biology
Year
2006
Tongue
English
Weight
591 KB
Volume
42
Category
Article
ISSN
1475-2689

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## Abstract The concerted action of TGF‐β and PDGF on a diploid human embryonic lung fibroblast cell strain (Flow 2002) grown in an homologous environment is investigated here. In sparse cultures, TGF‐β stimulates DNA synthesis over a broad concentration range (0.1‐10 ng/ml). Furthermore, it acts i