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Condensation of acylmetallocenes with acetonitrile

โœ Scribed by A. A. Koridze; A. A. Lubovich

Book ID
112421533
Publisher
Springer
Year
1972
Tongue
English
Weight
171 KB
Volume
21
Category
Article
ISSN
1573-9171

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Ritonavir (Norvirยฎ), 1, is an H1V-I protease inhibitor that recently received FDA regulatory approval for the treatment of HIV infection. I Retrosynthetically, Ritonavir requires the pseudosymmetric diaminoalcohol core unit 2. 2 We recently reported an efficient route for the large scale synthesis