Concurrent radiation therapy and chemotherapy followed by esophagectomy for localized esophageal carcinoma
β Scribed by Brian A. Bates; Frank C. Detterbeck; Stephen A. Bernard; Bahjat F. Qaqish; Joel E. Tepper
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 134 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0360-3016
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## Abstract ## Background Radiation therapy (RT) is commonly used in the management of patients with advanced (T3βT4) oropharyngeal squamous cell carcinomas. In recent years, based upon the metaβanalyses of randomized trials, chemotherapy administered concurrently with RT (chemoradiotherapy) has b
beginning on Day 1 and Day 21, concurrent with a split course of accelerated fractionation radiation (1.5 grays [Gy] twice daily, to a total dose of 45 Gy). All 1 Department of Hematology and Medical Onpatients were subsequently referred for surgical resection. A single, identical postcology, Clevel
Background and Objectives: Since the prognosis of patients with T4 squamous cell carcinoma (SCC) of the esophagus is extremely poor, an effective multimodal treatment needs to be established. Methods: Forty-five patients with SCC of the esophagus at the T4 classification of the disease but no hemato
Twenty-four previously untreated patients with primary inoperable squamous cell carcinoma of the esophagus showing no evidence of hematogenous metastasis were treated with concurrent chemotherapy and radiation therapy (CRT) followed by surgical resection if possible. The chemotherapy regimen consist