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Concomitant use of mirtazapine and phenytoin: a drug–drug interaction study in healthy male subjects

✍ Scribed by E. Spaans; M. van den Heuvel; P. Schnabel; P. Peeters; U. Chin-Kon-Sung; E. Colbers; J. Sitsen

Publisher
Springer
Year
2002
Tongue
English
Weight
112 KB
Volume
58
Category
Article
ISSN
0031-6970

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## Abstract ## Objective To assess the steady‐state pharmacokinetics of mirtazapine (30 mg/day orally) and amitriptyline (75 mg/day orally) during combined administration compared with that of either drug administered alone. To evaluate the tolerability and effects on psychometric tests of acute a