Concomitant use of mirtazapine and cimetidine: a drug–drug interaction study in healthy male subjects
✍ Scribed by J. M. A. Sitsen; F. A. Maris; C. J. Timmer
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 96 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Paroxetine inhibits cytochrome P(450) 2D6, which is involved in the metabolism of mirtazapine. The possible drug-drug interaction between two pharmacologically distinct antidepressants, mirtazapine and paroxetine, has been investigated in a randomized, three-way crossover study in 24 healthy male an
## Abstract ## Objective To assess the steady‐state pharmacokinetics of mirtazapine (30 mg/day orally) and amitriptyline (75 mg/day orally) during combined administration compared with that of either drug administered alone. To evaluate the tolerability and effects on psychometric tests of acute a