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Concise Synthesis of α-Substituted 2-Benzofuranmethamines and Other 2-Subsituted Benzofurans via α-Substituted 2-Benzofuranmethyl Carbocation Intermediates

✍ Scribed by Wongsa, Nikhom; Sommart, Ubonta; Ritthiwigrom, Thunwadee; Yazici, Arife; Kanokmedhakul, Somdej; Kanokmedhakul, Kwanjai; Willis, Anthony C.; Pyne, Stephen G.


Book ID
120171530
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
455 KB
Volume
78
Category
Article
ISSN
0022-3263

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## Abstract A new type of isocoumarins (=1__H__‐isochromen‐1‐ones=1__H__‐2‐benzopyran‐1‐ones), 4‐substituted 3,4‐dihydro‐3‐methoxyisocoumarins **2**, can be obtained by a one‐pot process from __α__‐substituted 2‐bromo‐__β__‐methoxystyrenes **1**. Thus, lithium 2‐(1‐aryl(or methyl)‐2‐methoxyethenyl)