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Concise synthesis of C2-symmetric trans-2,5-dioxymethylpyrrolidine derivatives by novel cyclization

โœ Scribed by Seiichi Takano; Minoru Moriya; Yoshiharu Iwabuchi; Kunio Ogasawara


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
139 KB
Volume
30
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis of both enantiomers of C2 symm
โœ Mukund P. Sibi; JianLiang Lu ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 347 KB

Lipase mediated sequential kinetic resolution has been employed to give both enantiomers of hans-2,5-bis(hydroxye~yl)pyrrolidine in optically pure form. The effect of different parameters on the ec and yields in these resolutions are also reported.